Aldosterone (chromatography)
Aldosterone is a hormone belonging to the mineralocorticoid group, which is produced in the adrenal cortex. It plays a key role in maintaining water and salt balance in the body by controlling sodium reabsorption and potassium excretion in the kidneys. Measuring aldosterone levels in the blood is necessary for diagnosing diseases associated with water and electrolyte metabolism disorders, as well as blood pressure disorders such as hyperaldosteronism.
High performance liquid chromatography with mass spectrometry (HPLC-MS) is used for accurate and reliable determination of aldosterone concentrations in blood. This method guarantees high accuracy and reproducibility of results, minimizing interference and errors that may occur with other methods. HPLC-MS also minimizes the influence of other hormones, making it ideal for accurate measurements.