Enterotoxin B (S.aureus), m81.

Patients with atopic dermatitis (AD) are often colonised by Staphylococcus aureus (S.a) strains secreting exotoxins such as Staphylococcus enterotoxins, enterotoxins A, B, C, D, E and toxic shock syndrome toxin (SEA, SEB, SEC, SED, SEE and TSST), where SEA and SEB appear to be the most important ones involved in IgE synthesis.

S.a is found on the surface of the skin, and it is thought that secreted toxins enter the skin through cutaneous lesions in AD. The density of S.a colonies in cutaneous lesions is 100-1000 times higher than in normal skin areas in AD patients. In addition, a significantly higher frequency of colonies is found on the apparently normal skin of patients with AD compared to the skin of healthy individuals. The prevalence of S.a colonisation in children with AD has been reported to be 93%, which is comparable to that in adults.

Determination of specific IgE in human blood to - Enterotoxin B (S.aureus), m81, shows the body's reaction to this allergen.

Test method: ImmunoCAP (Immunofluorescence on solid phase).

Units of measurement: kU/l

Biomaterial for the test: venous blood