Back

Cat rFel d 1, e94, IgG4 (ASIT monitoring)

Cat allergy is one of the most common causes of allergic rhinitis and asthma, especially in individuals sensitive to pets. The primary cat allergen is Fel d 1, a protein produced by the animal’s glands. For most allergic individuals, this protein is responsible for triggering severe symptoms.

Symptoms of Cat Allergy:

  • Nasal congestion and runny nose
  • Sneezing and nasal itching
  • Difficulty breathing, shortness of breath, wheezing
  • Choking episodes and coughing

Early allergy diagnosis and choosing the right therapy help prevent severe complications such as bronchial asthma.

Role of IgG4 in Allergy Treatment

Modern treatment methods, including allergen-specific immunotherapy (ASIT), are aimed at eliminating the root cause of allergy rather than just temporarily relieving symptoms. ASIT helps the body adapt to the allergen, reducing immune system overreaction.

The primary mechanism of ASIT is the induction of protective IgG4 antibodies, which block allergic reactions by competing with IgE.

An increase in specific IgG4 to rFel d 1 during treatment is an important indicator of therapy effectiveness.

Why Determine Specific IgG4 to rFel d 1?

Molecular diagnostics allows monitoring ASIT effectiveness by measuring IgG4 concentration to specific allergen components. The ImmunoCAP test for rFel d 1-specific IgG4 helps:

  • Confirm whether the immune system is responding to therapy
  • Evaluate the suitability of the ASIT medication
  • Decide whether to continue, modify, or discontinue ASIT

If IgG4 levels do not increase, this may indicate insufficient treatment efficacy or the need to adjust the vaccine composition.

Why Choose This Test?

  • ImmunoCAP technology ensures high accuracy and sensitivity.
  • It enables personalized evaluation of therapy response.
  • It helps make informed decisions for successful allergy treatment.

Visit our laboratory to assess the effectiveness of your treatment and receive expert recommendations for further therapy