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Levetiracetam (chromatography)

Levetiracetam (Keppra) is a modern second-generation antiepileptic drug prescribed for focal and generalized epileptic seizures. Determining its concentration in the blood helps to accurately select the dosage, ensuring effective treatment and reducing the risk of side effects and toxic effects.

High-performance liquid chromatography with a mass spectrometric detector (HPLC-MS) provides reliable measurement of even minimal levels of levetiracetam in blood samples. Thanks to its high sensitivity, the method allows for accurate control of the therapeutic concentration of the drug and monitoring of interactions with other drugs.