HSV I,II

It has been established that about 90 percent of the world's population is infected with the herpes virus, but only a small part of them have the virus manifesting itself clinically. Once in the human body, no matter how, the virus accumulates in the nerve nodes that are located along the spine and can be inactive there throughout a person's life unless certain factors provoke it and cause its activation (for example, a pronounced decrease in immunity) with subsequent generalization of the infectious process.

Herpes simplex virus (HSV) is a DNA-containing virus. There are 2 serotypes of the virus - herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2).

HSV-1 most often causes lesions of the mucous membrane of the oral cavity, eyes, and skin, and much less often - genital lesions, as well as herpetic encephalitis and pneumonitis. HSV-2 mainly causes genital lesions, neonatal herpes, and disseminated herpes.

Primary infection caused by HSV is particularly dangerous during pregnancy due to the high risk of spontaneous miscarriage, the development of severe lesions of the fetus and newborn, and the formation of congenital deformities.

HSV DNA is the main direct marker of the presence of herpes simplex virus in various biological environments of the body. The indication for the determination of HSV DNA is the presence of specific clinical manifestations, signs of intrauterine infection in newborns, a burdened obstetric and gynecological history, and examination of persons with immunodeficiency conditions. The study makes it possible to differentiate HSV-1 and HSV-2.

During pregnancy, if the mother has herpes, then there is a chance of a transplacental lesion of the fetus, mainly the newborn becomes infected when passing through the birth canal of the mother. With intrauterine infection of the fetus with the herpes virus, severe defects develop, especially of the nervous system, many of which are incompatible with life.

It is important to remember that in both men and women, a herpes infection can cause infertility.

The determination of herpes virus type I, II by polymerase chain reaction (PCR) is characterized by high sensitivity and specificity (98%). The principle of PCR is to identify a unique DNA fragment belonging to a given virus after repeated doubling of the studied genetic material in a test-tube.

In the OLYMP CDL branches, PCR analysis are made in REAL-TIME mode - this means that after each hardware cycle (amplification), the amount of DNA in the biomaterial is measured. This procedure reduces the probability of a false positive result to almost zero!

The test material is blood.