Determination of cocaine and its metabolites in urine (chromatography)
Cocaine is a powerful psychostimulant with a pronounced psychoactive effect. Its use can cause mild to severe poisoning, including the risk of overdose. Urine tests can detect not only cocaine itself, but also its main breakdown product, benzoylecgonine.
High-performance liquid chromatography with a mass spectrometric detector (HPLC-MS) is used for the qualitative detection of cocaine and its metabolites. The method is highly sensitive and accurate, ensuring reliable detection even at low concentrations in the sample.
Substances tested
- Cocaine
- Benzoylecgonine - main metabolite
- Cocaethylene - formed when cocaine and alcohol are taken simultaneously