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Ureaplasmosis IgG

The test relates to the serological diagnosis of genital infections. The test material is blood, in which antibodies to the pathogen are detected. Antibodies are components of the body's immune system that are produced to destroy a particular foreign protein-antigen. In this case, the antigen is Ureaplasma (Ureaplasma urealyticum).

There are several types of antibodies: IgA, IgD, IgE, IgG and IgM. However, the immune system cannot cope with ureaplasmas even with very high concentrations of antibodies. Each of these antibodies has its own function and its own period of occurrence. IgG is produced 15-20 days after infection and may persist in small amounts for a long time. After re-infection, the antibody titer rises again.

Ureaplasma causes an inflammatory disease – ureaplasmosis, which is accompanied by damage to the urethra, as well as the prostate gland in men and the vagina in women. Infection with ureplasmosis occurs mainly sexually, including the oral-genital route of transmission. The infection is transmitted to newborns from an infected mother, during the passage of the child through the birth canal. When planning pregnancy, parents need to be examined for this infection, since intrauterine infection of the fetus may occur during pregnancy, leading to severe consequences, especially during the period of active development of organs of fetus.

Factors contributing to infection with ureaplasma include:

  • Unprotected sexual contact and frequent change of sexual partners;
  • Taking broad-spectrum antibiotics;
  • Reduction of general and local immunity.

Clinical manifestations

In women:

  • Non-abundant vaginal discharge, almost colorless, without a specific odor;
  • Pain in the lower abdomen by the type of pain, which may be associated with the spread of the inflammatory process to the uterus and appendages;
  • Frequent urge to urinate unrelated to physiological need;
  • Pain and burning sensation during the act of urination;
  • Unpleasant, moderately painful sensations during sexual contact or after sexual intercourse.

In men:

  • Non-abundant, cloudy odorless discharge from the external urethra, most often in the morning after a long pause between acts of urination;
  • Moderate painful sensations during urination, burning sensations are less common;
  • Painful sensations in the scrotum, due to the penetration of infection into the testicle and appendage of the testicle.

In men and women:

  • During the transition of ureaplasmosis to chronic forms, infertility may occur, due to the development of the adhesive process, while in women the lumen of the fallopian tubes narrows, and in men the vas deferens "clogged".