Syphilis (Treponema pallidum abs)

The detection of total antibodies to treponema pallidum is the most comprehensive method of diagnosing syphilis. In contrast to other methods (microreaction, Wasserman test) it minimises the possibility of false-positive or false-negative results, as its aim is to detect specific antibodies against the syphilis pathogen in the patient's blood. In other cases, however, antibodies to nonspecific cardiolipin antigen are detected, which may be present in an organism that has never encountered the disease, which may be present in an organism that has never encountered the disease, which will not rule out a false-positive result.

Antibody summation means the detection of immunoglobulin class M and G (IgM, IgG), which is of great clinical importance. Only IgM are synthesized in response to syphilis if the patient has an acute phase of the disease or has been recently infected. The chronic form of syphilis implies the production of IgG.  The test results in a ratio of these antibodies, the value of which determines the test result.

Thus, syphilis diagnostics by determining specific total IgG/IgM antibodies to Treponema pallidum is the best price/quality ratio in comparison to other methods.