Нerpes virus IgG

The test relates to the serological diagnosis of infectious diseases. The test material is blood, in which antibodies to the pathogen are detected. Antibodies are components of the body's immune system that are produced to destroy a particular foreign protein-antigen. In this case, the antigen is herpes viruses type I and II.

There are several types of antibodies: IgA, IgD, IgE, IgG, and IgM. However, the immune system cannot cope with the herpes virus even with a very high concentration of antibodies. Each of these antibodies has its own function and its own period of occurrence. IgG antibodies are found in the majority of the adult population due to the widespread prevalence of the herpes virus. They indicate a chronic long-term process. For this reason, a single detection of antibodies has no clinical significance. It is necessary to monitor changes in the level of antibodies in dynamics: with an acute inflammatory process or exacerbation of a chronic one, an increase in the IgG titer occurs. IgG class antibodies remain in the blood for a year.

Herpes simplex viruses type 1 and type 2 are characterized by the destruction of the cells they infect. The place of localization of the virus in the body is nerve cells. The herpes simplex virus of the first type is extremely common. Primary infection occurs, in most cases, at preschool age. In the future, the probability of infection drops sharply. A typical manifestation of infection is a "cold" on the lips. However, with oral contact, genital damage is possible. Internal organs are affected only with a significant decrease in immunity. The virus can also affect the eyes (keratitis, conjunctivitis) and cause shingles.

Genital herpes is a disease of the genital organs that develops under the influence of the Herpes simplex virus. To date, 8 types of herpes virus are known, while genital herpes is caused by only two of them. These include HSV-1 and HSV-2. If we take into account all cases of infection of the genital organs with the herpes virus, then in about 80 percent of cases it is HSV-2 that is detected, and only in 20 percent of cases HSV-1. The virus of the first type more often causes the very first episode of genital herpes. Repeated manifestations of genital herpes are almost always associated with HSV-2.

It has been established that about 90 percent of the world's population is infected with the herpes virus, but only a small part of them have the virus manifesting itself clinically. Once in the human body, no matter how, the virus accumulates in the nerve nodes that are located along the spine and can be inactive there throughout a person's life unless certain factors provoke it and cause its activation (for example, a pronounced decrease in immunity) with subsequent generalization of the infectious process.

The main route of transmission of genital herpes is sexual, while it is transmitted through all types of sexual contact (vaginal, oral, anal). At the same time, in 50 percent of cases, the sexual partner has absolutely no clinical manifestations of genital herpes. Infection through personal hygiene products is a fairly rare phenomenon, the chance increases if there is damage on the skin with which an object infected with the virus comes into contact. During pregnancy, if the mother has herpes, then there is a chance of a transplacental lesion of the fetus, mainly the newborn becomes infected when passing through the birth canal of the mother. With intrauterine infection of the fetus with the herpes virus, severe defects develop, especially of the nervous system, many of which are incompatible with life.

Toxoplasmosis is a potentially dangerous group of TORCH infections for fetus development (toxoplasma, rubella virus, cytomegalovirus, herpes).