To the news listNew! Immunohistochemical Study of p53 (TP53)
CDL OLIMP is expanding its range of immunohistochemical tests and introduces a new study - assessment of p53 (TP53) protein expression by immunohistochemistry (IHC).
The p53 protein is one of the key regulators of the cell cycle and plays an important role in preventing tumor transformation of cells. Alterations in p53 expression may indicate the presence of genetic abnormalities associated with the development of malignant neoplasms.
When is this test recommended ?
- To clarify the nature of a tumor process;
- In the diagnosis of precancerous and malignant neoplasms;
- As part of an extended immunohistochemical evaluation;
- For the differential diagnosis of tumors of various localizations;
- To assess prognostic factors of the disease.
Diagnostic significance of p53
TP53 gene mutations are among the most common genetic alterations found in malignant neoplasms. Assessment of p53 protein expression helps pathologists interpret morphological changes more accurately and establish a diagnosis in complex clinical cases.
Biomaterial
The study is performed on histological material prepared in the form of paraffin blocks.
Advantages of the test
- High diagnostic value in the comprehensive evaluation of tumor processes;
- An additional tool for refining the morphological diagnosis;
- Assistance in assessing the biological characteristics of a neoplasm;
- Improved diagnostic accuracy in the interpretation of histological changes.
For additional information about the test and guidelines for submitting biomaterial, please contact your personal manager or visit the nearest OLIMP CDL branch.
