Anizakida, p4

Anisakis spp. They are parasitic nematodes of many marine species that are distributed throughout the world and can infect people when eating raw, undercooked or processed foods.

Anisakis infection causes "anisakiosis", a clinical disease with non-specific clinical manifestations, including:

epigastric pain, nausea, vomiting, abdominal distension with severe pain and sometimes hypersensitivity or anaphylaxis.

Anisakiosis is a common form of food poisoning, with tens of thousands of cases reported worldwide.

Sensitized individuals may also develop Anisakis-induced:

asthma, rhinoconjunctivitis, dermatitis, and secondary gingivostomatitis after contact with the proteins of dead larvae.

Approximately 26 allergens with different biological functions have been characterized in Anisakis spp. Today, many of them are preserved and are highly resistant to heat and digestive enzymes.

The main allergens include:

Anise 1, Anise 7, Anise 12 and Anise 14,

while secondary allergens are:

Anise 4, Anise 5, Anise 6, Anise 8, Anise 9, Anise 10, and Anis 11.

Anis 2 (paramiosin) and Anis 3 (tropomyosin) are considered to be low-specificity panallergens.

The determination of specific IgE in human blood to - Anisakid, p4, shows the body's reaction to this allergen.

Research method: ImmunoCAP method (Immunofluorescence in the solid phase)

Units of measurement: kU/l

Biomaterial for analysis: venous blood